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In ovariectomized mice, a standard model for studying menopausal metabolic changes, MOTS-C administration reduced fat accumulation and improved insulin sensitivity

Efficacy and safety of once weekly semaglutide 24 mg for weight management in a predominantly East Asian population with overweight or obesity (STEP 7): a double-blind, multicentre, randomised controlled trial

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Outcomes future studies should measure MRI activity: New or enlarging brain and spinal cord lesions