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The combination of GLP-1's effect on insulin sensitivity and strength trainings ability to improve it can create a synergistic effect, making the body more efficient at using glucose and promoting fat loss while preserving muscle

Targeting intermediary metabolism Farnesoid X receptor (FXR) agonists The nuclear FXR agonists may treat MASLD through various mechanisms, including alleviating insulin resistance and exerting direct anti-inflammatory and antifibrotic effects on MASH in both mouse models and human tissues

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