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For example, studies using radiolabeled exenatide have shown that it can readily enter the mouse brain, though this central uptake appears to diminish at higher doses (Kastin and Akerstrom, 2003)

Many patients on GLP-1 therapy are eating less overall, which means dietary calcium intake may drop below the threshold needed for bone maintenance

The Permanente Journal, 26 (2), 8997

Glucagon-Like Peptide-1 Receptors in the Brain: Controlling Food Intake and Body Weight

[DOI] [PubMed] [Google Scholar] 38.Billington CJ, Briggs JE, Link JG, et al