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Risk of bias: all four RCTs were rated low risk by RoB2 (with some concerns for open-label outcome ascertainment in three trials, a domain-specific issue that does not alter the overall RoB2 category from low)

Researchers are exploring whether GLP-1 medications used for diabetes and weight loss could treat Alzheimers and addiction.

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As weight loss research progresses, supplement and food brands expect more consumers will seek to optimize the semaglutides' effectiveness and manage their negative symptoms.

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