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Description
In theory, this pharmacological profile might allow orforglipron to maintain its effectiveness longer than traditional full GLP-1 receptor agonists
Lancet 39818111824
The GLP-1 receptor activation suppresses appetite, slows gastric emptying, and enhances insulin secretion
How long does it take to see results with semaglutide for weight loss
That is a clinically meaningful secondary benefit for patients with type 2 diabetes, but it is not the same as the weight loss observed in obesity-specific trials at higher doses
