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How to Stop Nausea from GLP-1 Weight Loss Medications Because semaglutides and other GLP-1 drugs slow down the movement of food as it moves from the stomach into the digestive tract, you may feel nausea quite often as you get used to how these medications work

Panther EJ, Lucke-Wold B

Medications like semaglutide (Ozempic) and liraglutide (Saxenda) are gaining attention for their effectiveness in aiding weight loss

Patients may need a more careful discussion if they have a history of: Previous NAION in one eye Significant optic nerve crowding Diabetes with vascular complications Sleep apnea, especially untreated sleep apnea High blood pressure or low nighttime blood pressure Cardiovascular disease Sudden unexplained vision loss in the past This does not automatically mean a GLP-1 medication is unsafe, but it does mean the patient should have a personalized risk-benefit discussion with their medical provider

95% CI, 0.56 to 0.84) (eTable 3)