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Description
Liraglutide is based on the native GLP-1 (737) sequence with a (conservative) substitution of lysine at position 28 with arginine

These two cannot be simultaneously true

J Biol Chem 267(11):74027405
doi: 10.3390/jcm8111992 67 ViriliCTrimboliPCentanniM

The medication lineup is competitive but comes with important caveats
