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Cost was noted to be a significant factor for patients in the USA compared to other EU countries, with 48.6% of patients reporting discontinuation due to cost in the USA vs

However, tirzepatide's effect on gastric emptying can alter the absorption of concomitant oral medications

And there is no clear path forward for GLP-1 coverage in Medicare after 2027 if the Medicare GLP-1 Bridge is not extended further and the BALANCE Model is not implemented

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