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An increasingly common precision medicine approach applied in AD/ADRD clinical trials is the use of enrichment designs (described earlier in this chapter) that limit recruitment based on biomarker or other screening results to better target AD/ADRD interventions to at-risk populations

It is an investigational drug in clinical trials

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However, the GLP-1R is also involved in adipogenesis in the periphery, which may account for this discrepancy (Challa et al., 2012)

GLP-1 weight loss emotional benefits and mental health improvements The emotional benefits are often profound, including reduced stress, improved self-esteem, and a greater sense of well-being stemming from successful weight loss and restored control over eating