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Tirzepatide Is Sufficient (Stay Put) If: You're close to your target weight: If tirzepatide has gotten you 8090% of the way to your goal, switching drugs mid-course introduces titration disruption and new side effects for a marginal numerical gain

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10.1136/bmjopen-2018-024065 [DOI] [PMC free article] [PubMed] [Google Scholar] 48.Gudbergsen H, Overgaard A, Henriksen M, Waehrens EE, Bliddal H, Christensen R, Nielsen SM, Boesen M, Knop FK, Astrup A, Rasmussen MU, Bartholdy C, Daugaard CL, Ellegaard K, Heitmann BL, Bartels EM, Danneskiold-Samsoe B, Kristensen LE (2021) Liraglutide after diet-induced weight loss for pain and weight control in knee osteoarthritis: a randomized controlled trial