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Recent studies highlight how GLP-1 receptor agonistsincluding Semaglutide (Ozempic, Wegovy) and Tirzepatide (Mounjaro, Zepbound)exhibit powerful anti-inflammatory effects

One possible explanation is the relatively small sample size of these subpopulations, as only approximately 24% of participants were of Black or Asian race

Safety analysis of compounded GLP-1 receptor agonists: A pharmacovigilance study using the FDA adverse event reporting system

81 It has been hypothesised that insulin moves through the blood-brain barrier into the brain and acts as a neuropeptide positively regulating satiety, olfaction, cognition and memory as well as regulating systemic functions such as hepatic glucose production

Among the hormones implicated in this axis, glucagon-like peptide 1 (GLP-1) has gained attention due to its dual metabolic and neuroregulatory actions