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HOMA-IR improvements were also substantial, indicating meaningful restoration of insulin sensitivity

To overcome these limitations, a Safety-by-Design approach has emerged

Explore alternative weight loss solutions Depending on availability and cost, we may need to look at other treatments, including other weight loss medications, lifestyle strategies, or non-medication options

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While no established willingness-to-pay threshold exists for weight loss outcomes at 68 weeks, semaglutides lower cost of control and higher efficacy versus liraglutide suggest it is likely to be a cost-effective treatment option