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GLP-1 receptor agonists increase the risk of gallstone formation and related biliary complications, with liraglutide showing approximately 1.6-2.1 times high...

Conclusions These data demonstrate for the first time the potent effect of semaglutide in reducing voluntary alcohol intake in non-human primates and further substantiate the need for clinical trials investigating the effect of semaglutide in patients with alcohol-use disorder.

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The potential biological mechanisms underlying their influence on cancer risk are complex, involving metabolic regulation, direct antitumor effects, immune modulation, and epigenetic changes
