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GLP-2 (Tirzepatide) is a dual incretin receptor agonist widely utilized in preclinical research involving metabolic regulation, incretin signaling, and energy balance-associated biochemical pathways

Also known as GLP-1 medications, these popular drugs were initially approved to treat type 2 diabetes, but doctors quickly discovered that they also facilitated significant weight loss thus, the birth of the weight-loss drug craze.

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Those drugs have about a decade of basic science on animals, and now

The 2025 Nobel Prize in Physiology or Medicine is awarded to Joel Habener, Svetlana Mojsov, and Jens Juul Holst for their discovery and development of GLP-1based therapeutics, which have revolutionized the treatment of diabetes and obesity worldwide. | 29 comments on LinkedIn