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Clinical data on semaglutide and tirzepatide shows average weight loss of 12 lbs/week during dose escalation, with steeper losses in months three through six as the dose reaches maintenance

The main effect of endogenous GIP regarding weight is primarily on adipose tissue, where it promotes positive energy balance

However, its suitability varies from person to person, based on individual health profiles and specific medical conditions

63.8%), lower rates of chronic kidney disease (10.3% vs
