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After Dose Increases Temporary return of symptoms is common, usually milder than initial onset
The medication is administered as a once-weekly subcutaneous injection, with a recommended starting dose of 2.5 mg for 4 weeks, then 5 mg, with stepwise escalation to a maximum of 15 mg as tolerated, according to the UK SmPC

10.1016/j.peptides.2006.05.011
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