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Liraglutide (25 nmol/kg/day) treatment significantly reduced the inflammatory response in the cortex as measured by the number of activated microglia and prevented degenerative processes in a 7-month-old APP SWE /PS1 E9 mouse model of Alzheimer's disease [86]

[DOI] [PubMed] [Google Scholar] 151.Nuijten M.A.H., Eijsvogels T.M.H., Monpellier V.M., Janssen I.M.C., Hazebroek E.J., Hopman M.T.E

In addition, polyGLP-1 treatment promoted BMSC differentiation to osteocytes to the detriment of adipocytes and also induced anti-inflammatory M2 polarization of bone marrow-derived macrophages [63]

To understand the long-term safety and chronic effectiveness of these treatments, these studies will be essential
