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Recently, the GLP-1 RA semaglutide was reported to reduce cardiovascular events in ASCVD patients with overweight or obesity even in the absence of diabetes mellitus

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Purpose of Review: This article summarizes the medical management of obesity with an emphasis on incretin-based therapeutics that target the neuro-hormonal basis of obesity.Recent Findings: Medications that mimic the effect of incretins, a group of peptide hormones released in response to nutrient intake that regulate appetite, result in potent and durable weight loss

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Despite safer natural options, women are resorting to off-label use of GLP-1 drugs for faster weight loss to ensure better management of PCOS.

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The digestive comfort blend targets the most common GLP-1 side effects

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