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This could be due to mechanisms such as the anti-inflammatory effects of GLP-1 agonists, their influence on metabolic pathways, or their ability to modulate cancer cell proliferation and apoptosis

Maybe they injected 10 mg

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Abbreviations ACEi: Angiotensin-converting enzyme inhibitor AE: Adverse event ARB: Angiotensin receptor blocker BMI: Body mass index BP: Blood pressure CI: Confidence interval CKD: Chronic kidney disease CV: Cardiovascular CVD: Cardiovascular disease CVOTs: Cardiovascular outcome trials DPP-4i: Dipeptidyl peptidase-4 inhibitor eGFR: Estimated glomerular filtration rate ERR: Estimated risk ratio ETD: Estimated treatment difference FAS: Full analysis set GLP-1RA: Glucagon-like peptide-1 receptor agonist HbA 1c : Glycated hemoglobin HHF: Hospitalization for heart failure HR: Hazard ratio I 2 : Inconsistency across estimates LDL: Low-density lipoprotein MACE: Major adverse cardiovascular event MDRD: Modification of Diet in Renal Disease MET: Metformin MI: Myocardial infarction N/A: Not available R: Events per 100 patient-years observed RHR: Ratio between the hazard ratios in metformin vs no-metformin groups SD: Standard deviation SGLT-2i: Sodiumglucose cotransporter-2 inhibitor TIA: Transient ischemic attack TZD: Thiazolidinedione References Rao Kondapally Seshasai S, Kaptoge S, Thompson A, Di Angelantonio E, Gao P, Sarwar N, et al