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The doses are different also

Evidence-based practice supports choosing one agent and optimizing its dose before contemplating polypharmacy

In diabetic mice, D13 and D41 demonstrated prolonged hypoglycemic effects

( 10.1038/s41598-020-59799-2) [DOI] [PMC free article] [PubMed] [Google Scholar] Del Prato S, Kahn SE, Pavo I, Weerakkody GJ, Yang Z, Doupis J, Aizenberg D, Wynne AG, Riesmeyer JS, Heine RJ, et al

Fitch A et al
