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Crosstalk of reactive oxygen species and NF-B signaling

Case reports and small sample studies show early weight loss

58 Both STEP 1 and SURMOUNT-1 trials included dual-energy X-ray absorptiometry (DXA) body composition assessments in a subset of participants

All patients should reduce premeal insulin by 50% to lessen the risk of insulin-induced hypoglycemia, monitor blood glucose frequently, and contact their health care provider if symptoms of nausea and/or hypoglycemia are severe or unusually persistent and when the dosage of pramlintide or insulin is changed

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