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Not all patients achieve clinically significant weight loss, and there is currently no reliable method to predict which individuals will respond optimally

Initial and continuation approval: 16 weeks (oral and injectable)

[DOI] [PMC free article] [PubMed] [Google Scholar] 135.Thong KY, Jose B, Sukumar N, Cull ML, Mills AP, Sathyapalan T, Shafiq W, Rigby AS, Walton C, Ryder RE

Overweight and obesity are defined by the World Health Organization as having a body mass index (BMI) 25 253 million global disability-adjusted life years, 6.5 million deaths and almost 62 million years lived with disability from CKD, resulting in a higher global BMI-related burden for CKD than for other conditions traditionally linked to obesity, such as colorectal cancer [4]

& Schaeffer, J