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The 12.5 to 15 mg band adds modestly to average weight loss but widens the high-response tail

10.1001/jama.2020.14545 [DOI] [PMC free article] [PubMed] [Google Scholar] 5

Retatrutide is the unimolecular triple agonist furthest in development and data from phase 2 trials suggests that this may soon become the most potent weight-lowering pharmacotherapy to be licenced

Studies suggest Tirzepatide may lead to greater weight loss than GLP-1 for some patients

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