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Ozempic Face refers to a phenomenon where rapid weight loss due to semaglutide treatment causes significant facial fat loss and subsequent skin laxity

These medications provide several benefits to the body: they boost insulin release when blood sugar is high, lower glucagon production, slow down gastric emptying and help reduce hunger by targeting the GLP-1 receptors in the brain [1315]
Among people using the drugs without diabetes, discontinuation rose to around 65%

They followed 173 RA patients with overweight or obesity who were prescribed and actually took a GLP-1 medication (semaglutide or tirzepatide) between 2018 and 2024, and compared them to 42 patients who were prescribed one but never took it

But lifestyle adoption of GLP-1s has already exceeded drugs like Adderall by about 5% in a span of only a few years
