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Description
The established and emerging roles of GLP-1RAs critically examine their efficacy, safety, financial burden, and disparities in access, limitations, and prospects
Trelagliptin is approved in Japan since 2015
Clinical efficacy is equivalent when dosed appropriately
It is approved for treating hyperglycemia in patients with T2DM in many countries (105, 106)
The nociceptor ion channel TRPA1 is potentiated and inactivated by permeating calcium ions
