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Psoriatic arthritis and obesity: a review of clinical burden and considerations for comprehensive care, RMD Open, 12 , 3, (e006577), (2026)

L., Giles, C

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Studies using whole-body GIPR KO mice [99], GIP-secretion-deficient mice [100], whole-body administration of GIPR antagonists (see below), and GIP immunoneutralization [101] have shown that fat accumulation and insulin resistance associated with high-fat intake are suppressed by inhibition of GIP signaling