is tirzepatide a glp-1 receptor agonist Effects of tirzepatide, dual GIP and agonist, on blood pressure, cardiac function, and sympathetic nervous system in stroke-prone spontaneously hypertensive rats PDB-101: Molecule of the Month:

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- **Curb appetite:** Helping individuals feel full, potentially leading to reduced food intake

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Other combinations of entero-pancreatic hormones including cagrisema (GLP-1/amylin RA) and the triple agonist retatrutide (GLP-1/GIP/glucagon RA) have also progressed to phase 3 trials as obesity treatments and early data suggests that may lead to even greater WL than tirzepatide