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Some data suggest that pharmacological inhibition of sweet taste receptors blunt GLP-1 responses to nutrients (217), but other studies found no impact of sweet taste receptor agonists on GLP-1 secretion in humans (146, 178) or in in vivo or ex vivo studies in rats (208)

doi: 10.1016/j.molmet.2019.09.010 [DOI] [PMC free article] [PubMed] [Google Scholar] 12

Prescribing of AOM tirzepatide (Zepbound) was observed in the first month of availability in pharmacies, December 2023

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