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Severe, persistent upper abdominal pain radiating to the back, accompanied by nausea and vomiting, requires immediate medical assessment and discontinuation of the medication

If you hit a plateau on three times weekly dosing, returning to daily dosing is a reasonable first step before escalating the dose

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Engaged international society-nominated panels included paediatrics, endocrinology, gynaecology, primary care, reproductive endocrinology, obstetrics, psychiatry, psychology, dietetics, exercise physiology, obesity care, public health and other experts, alongside consumers, project management, evidence synthesis, statisticians and translation experts

4) the study type was a randomized controlled trial