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However, its unclear if small amounts of the drug can actually combat inflammation, University of Toronto professor Daniel Drucker told the Post

Early post-marketing surveillance and case reports raised initial concerns, prompting extensive investigation through randomised controlled trials, observational studies, and meta-analyses

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When compared at doses of 0.5, 5 and 50 nmol kg 1 in the same study, GLP-1RA/tesaglitazar also improved glucose tolerance with superior efficacy relative to the fixed dose combination of the GLP-1RA + tesaglitazar, but with decreasing superiority with increased concentrations (Fig