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The final reduction and discontinuation The transition from 2.5 mg to zero is psychologically the hardest step, even though the pharmacological difference is relatively small

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All of these factors play a vital role in supporting a sustainable weight loss journey

The lack of comprehensive safety data for berberine supplements means that unexpected interactions or adverse effects cannot be ruled out, emphasising the importance of medical supervision

Serious adverse events like pancreatitis or gallbladder issues are rare (less than 2% in clinical trials) but require immediate medical attention if they occur