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It has quality-of-life applications related to skin health, as research supports its ability to tighten loose skin, improve skin firmness, reduce photodamage, promote wound healing, and more.41 Insulin: Insulin is a quality-of-life treatment for managing blood sugar

Early research on injectable semaglutide is promising

A case series published in the American Journal of Health-System Pharmacy documented allodynia specifically associated with semaglutide, and a Cureus publication detailed dysesthesia and allodynia with both semaglutide and tirzepatide

Clinical decisions should follow from controlled studies, triangulated with other clinical and preclinical evidence, the researchers wrote in the December commentary

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