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Seeds has also gathered peer-reviewed research that shows how GLP-1 receptor agonists also have the potential to effectively address the root causes of heart disease, certain cancers, neurodegenerative diseases, autoimmune disorders, arthritis, and other disease conditions

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Younger users and men are especially prone to quitting, raising concerns since discontinuation often leads to weight regain.

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In this Review, the authors discuss neuromodulation therapies in relation to current knowledge of the nerve circuitry, provide insights into possible mechanisms and explore reasons for limited success and how effectiveness might be improved.