swapping from semaglutide to tirzepatide Switching Tirzepatide vs Semaglutide: Key Differences
Description
Indications and Contraindications: Indications include individuals with a body mass index (BMI) of 30 or higher or those with a BMI of at least 27 with one or more weight-related comorbidities, such as hypertension or type 2 diabetes

1 While the trial was not designed as a weight loss trial, participants in the trial who received semaglutide still lost an average of 9.4% of total body weight which was sustained throughout the trial
They typically prescribe the smallest effective dose that achieves desired results while minimizing potential side effects

Beyond 48 Weeks: What We Can Infer The Phase 2 data only covers 48 weeks, so there is no published Retatrutide-specific evidence past that mark

However, maintaining consistent dosing helps support the best long-term results
