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Pyruvate dehydrogenase kinase (PDK) inhibits PDH activity [24]

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Lack of Nrf2 in this model also restored basal protein oxidation levels (measured by an increase in 4-hydroxynonenal modification, a byproduct of lipid peroxidation)

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GSH eased the overexpression of TRPA1 by oxaliplatin Both qRT-PCR and immunofluorescence were performed to determine the expression levels of TRPA1 in the DRG after every injection and behavioral analysis