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formulated a di-block polymer of Poly-lactic-co-glycolic acid (PLGA) and hetero bi-functional COOH-PEG-NH 2 , embedded with an imidazotetrazine alkylating agent (TMZ), and conjugated to a ligand (polysorbate-80/transferrin) and a stem cell targeting moiety (anti-nestin antibody)

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After washing with PBS until clear, the wells were air-dried, and 150 L 33% acetic acid was added to solubilize the crystal violet

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