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In diabetic mouse models, metformin has been shown to reduce renal NLRP3 expression and urinary MCP-1 levels

This highlights a crucial behavioral aspect that needs to be addressed comprehensively in the pre-transplant evaluation and post-transplant follow-up [116]

Noonan syndrome A dysmorphic syndrome associated with phenotypical congenital heart defects and short stature (OMIM 615355)

To induce maturation towards macrophages, Phorbol 12-myristate 13-acetate (PMA) (Lot: 16561-29-8, absin, China) was added to complete medium comprising RPMI-1640 (Gibco, Cleveland, TN, USA), supplemented with 10% fetal bovine serum (FBS

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