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Inhibition of radiation-induced DNA-protein cross-link repair by glutathione depletion with L-buthionine sulfoximine

In response to systemic inflammation, and in particular in response to elevated IL-6 levels, the liver produces (C-reactive protein) CRP, a protein that binds to dead or dying cells to activate the complement system

J Nutr 104:345378

Expected phenotype Reduced GSH, oxidative damage Human disease relevance Involved in liver disease, neurodegeneration Model applications Glutathione metabolism, antioxidant defense Keywords: GSH synthesis, Oxidative stress, Detox Availability & Delivery: Cryo-recovery using in-house SOPF facilities Worldwide delivery by professional breeders