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Description
4M + S4F), indicating AST reduction is indeed caused by clearance of senescent cells

Wien Klin Wochenschr 2000;112(14):617-623

Motor symptoms such as tremor, stiffness, and slowed movement are the most visible signs of the disease, though nonmotor symptoms are also common

Nucleosides Nucleotides Nucleic Acids 20 , 10911098 (2001)

A freezer that cycles between -15C and -25C provides a very different storage environment than one that maintains a steady -20C
