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Most information comes from animal studies (where doses are scaled by body weight) and anecdotal reports from users
The glutathione defense system in the pathogenesis of rheumatoid arthritis
Cells were also treated with 35 mM of mannitol to exclude the possible effect of osmolarity [24]

2019 doi: 10.1101/492652

Abnormal lab studies showing elevated BUN, creatinine, glucose, or lactic acid are acceptable
