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The clinical experiment was performed using PS with topical application on human skin in vivo , just as Kim's study (80)

Figure 2 2.2.1 CD8+ T cells CD8+ T cells, key immune effector cells in the TME, are involved in tumor clearance, as well as in responding to viral infections and other pathological conditions ( in vitro studies have demonstrated that glutamine deprivation can promote the differentiation of memory CD8+ T cells, facilitating the development of long-lasting immune memory ( in vivo inhibition of glutamine metabolism helps prevent CD8+ T cell exhaustion, sustaining their long-term effector functions ( 2.2.2 CD4+ T cells Upon antigenic stimulation, CD4+ T cells undergo metabolic reprogramming, activating pathways critical for their proliferation and differentiation ( via epigenetic mechanisms

The data generated from these studies aims to contribute to the broader scientific knowledge base, potentially leading to new treatments or medical advancements

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Inhibition of JNK by a peptide inhibitor reduces traumatic brain injury-induced tauopathy in transgenic mice
