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In terms of mechanism of action, the effects of EA in treating POI exhibit significant multisystem synergistic characteristics, potentially exerting its effects through multiple pathways such as the vagus nerveovarian axis, HPO axis, and the emerging gut microbiotaovarian axis

GGT is found in many tissues, including: Liver Bile ducts Kidneys Pancreas Intestines Brain Despite its widespread presence, the liver is the primary contributor to circulating GGT levels , which is why it is commonly associated with liver health

While using standard clinical criteria such as the UK Parkinson's Disease Society Brain Bank criteria can improve accuracy, it still only reaches slightly above 80% accuracy during the first visit

On the other hand, research should focus on the development of aptamers with improved binding affinity and specificity for exosome biomarkers, as well as integrating aptamers into portable, low-cost detection systems

As an example, it is important to highlight that the number of papers reporting positive results from the usage of l-Cys in medicines and nutritional therapies has significantly increased during the last decade