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In the skin and blood, the area under the curve (AUC) for SH-MN was 1.43 and 1.63 times that of SH-G, respectively, indicating that microneedles enhanced SINs transdermal penetration and increased its bioavailability (175)

cis-Polyunsaturated Fatty Acids Induce High Levels of Superoxide Production by Human Neutrophils

This dramatically increases the free, receptor-available fraction
