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Description
Upon migration to peripheral tissues, monocytes differentiate into either dendritic cells or macrophages
Native IGF-1 has a frustrating pharmacokinetic limitation: it binds tightly to a family of IGF binding proteins (IGFBPs, particularly IGFBP-3) that sequester it in circulation and keep its free half-life to roughly 15-20 minutes
doi: 10.1128/IAI.01481-08 95 LabordeJDeraeveCBernardes-GenissonV
I was always afraid of that
10.1016/j.jamda.2020.02.022 160
