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We defined Sepsis-3 by i.) suspected infection (e.g., administration of antibiotics or body fluid culture) & ii.) organ dysfunction (e.g., 2 or more SOFA points) in the first 6 hours of care

Effect of matrices and additives on phosphorylated and ketodeoxyoctonic acid lipids A analysis by matrix-assisted laser desorption ionization-mass spectrometry

Cell Mol Immunol 12:523

Interestingly, VCAM-1a protein expressed by endothelial cells in the BBB that is involved in peripheral immune cell recruitmentexpression increases in the aged brain, and the application of anti-VCAM-1 antibodies reduces microglial reactivity and improves memory and learning in aged (19-month-old) mice (Yousef et al., 2019)

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