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This happens because a lack of B12 disrupts their normal development, and its a major clue that something is amiss

Experimental injury, a surgical incision in the plantar aspect of the rat hind paw, leads to a remarkable reduction in paw withdrawal threshold to mechanical stimuli for several days, representing mechanical hyperalgesia [10]
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This modulation appears selective, as AOD 9604 does not activate the growth hormone receptor or induce downstream IGF-1 signaling
