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Furthermore, in addition to OXT regulation, a lipopolysaccharide (LPS)-induced depression-like behavior mouse model demonstrated that inhibiting CD38 improved neuroinflammation, microglial activation, synaptic defects, and Sirt1/STAT3 signaling, thereby improving depression-like behavior [13]

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We did not observe signs of improved glycolytic capacity at the time of analysis, which may relate to the longitudinal treatment for a week, in which the viral-specific CD8 + T cells could have already adapted to a lower viral load

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