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The studys use of beta-3 receptor knockout mice confirmed the specificity of the lipolytic mechanism, demonstrating that the peptides effects occur exclusively through this peripheral fat tissue pathway
doi: 10.1055/s-0038-1667310

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Interestingly, apigenin could induce apoptotic cascades selectively to glioblastoma cells, barring normal astrocytes, which strengthens the appeal of apigenin [172]

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