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Clonogenic assay was done as we described previously [76]
The iron-rich milieu induces upregulation of the iron transporter DMT1 through two sequential mechanisms: First, unbound iron activates hypoxia-inducible factor-1 (HIF-1), which directly binds to the DMT1 promoter to enhance its transcription (Ingrassia et al
doi: 10.1016/j.taap.2011.03.017
K.ChandelH
54 , e13028 (2021)
