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Resistance is futile: Overcoming resistance to targeted therapies in lung adenocarcinoma

This work was funded by the Austrian Science Fund - FWF - Project number No

Since NAD + is present in only catalytic amounts in the cell and is an essential cofactor for glycolysis (and other reactions), there must be a mechanism for regeneration of NAD + if glycolysis is to continue

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In recent years, the roles of oxidative stress and mitochondrial dysfunction in the progression of OA have garnered significant attention (Suantawee et al., 2013